News
Evo 2 Reveals Evolution's Genetic Secrets
1+ hour, 34+ min ago (485+ words) An AI model trained on tens of thousands of species can understand genetic code as never before, offering vast potential for precision medicine. Evo 2, published in Nature, could help pinpoint disease-causing genetic variants, inform therapeutic design, and potentially even reshape…...
HeFH Base Editor Shows Promise in Chinese Clinical Trial
22+ hour, 56+ min ago (551+ words) HeFH Base Editor Shows Promise in Chinese Clinical Trial'Inside Precision Medicine The global clinical race to rewrite cholesterol biology continues to heat up. A single infusion of experimental gene editing therapy has cut LDL cholesterol by more than 50% in patients…...
CD70-Directed HIT Cell Therapy Could Boost Immunotherapy for Solid Tumors
1+ day, 3+ hour ago (341+ words) Curing solid tumors is not easy, but this work solves one piece of the puzzle," said senior author Michel Sadelain, MD, PhD, director of CICET, and a pioneer in the development of current CAR T therapies. The properties of an…...
Genetics of Psychiatric Disorders Not as Specific as Previously Thought
1+ day, 16+ hour ago (360+ words) Research led by Virginia Commonwealth University shows people may have an increased risk for developing a psychiatric or substance use disorder due to their genetic family history, but it may not be the same disorder experienced by their relatives. As…...
Brain Blood Flow Markers Detect Early Signs of Alzheimer’s
1+ week, 1+ hour ago (193+ words) Amyloid and tau are often considered the primary players in Alzheimer's disease, but blood flow and oxygen delivery are also critical," said Amaryllis A. Tsiknia, PhD candidate at USC and lead author of the study. Our results show that when the…...
Alicia Zhou: The Dark Matter for Cancer Immunotherapy Translation
1+ week, 8+ hour ago (725+ words) The Cancer Research Institute CEO discusses how the nonprofit is sharing data to accelerate precision cancer care from genomics to immunotherapy By Jonathan D. Grinstein, PhD IPM: What is the role of nonprofit organizations in advancing medicine, and how does it…...
Riding the Gene Therapy Rollercoaster Into 2026
1+ week, 5+ day ago (1744+ words) It has been a tough, if interesting, year for the gene therapy space, with many ups and downs culminating in some optimism and increased funding and investment as 2025 drew to a close. A continued financial slump in biotech investment after…...
When Antibodies Become the Drug Factory
1+ week, 5+ day ago (568+ words) By Mike May, PhD At Sanofi, Christian Mueller, PhD, vice president and global head of genomic medicine, frames the challenge of antibody gene therapy in three words: delivery, durability, and safety. Each is familiar from gene therapy's history, but antibodies…...
Underdiagnosed Four-Repeat Tauopathies PSP and CBD Identified by MRI Tool
2+ week, 1+ day ago (243+ words) Although they may look very similar clinically, at the brain level, PSP and CBD damage the brain in different ways," said Ill'n-Gala. These differences are reflected on MRI, and by combining them into a signature, we can much better determine…...
Machine Learning Flags Cell Transplantation Risks
2+ week, 1+ day ago (547+ words) An artificial intelligence tool can identify potential complications after bone marrow or stem cell transplantation before symptoms arise, which could allow for more accurate monitoring of patients and pre-emptive treatment. The BIOPREVENT algorithm combines machine learning with immune biomarkers and…...