13+ hour, 38+ min ago   (625+ words) Pancreatic cancer remains one of the most formidable diagnoses in modern medicine, and a new case report is drawing attention for a strikingly inventive solution to one of its most stubborn clinical problems....

14+ hour, 14+ min ago   (529+ words) Every cell in the brain carries essentially the same genome, yet the same gene can produce a startling variety of RNA molecules. Through a process called alternative splicing, segments of a gene’s transcript can be included, skipped, or rearranged, generating…...

19+ hour, 10+ min ago   (649+ words) A new health economic analysis has found that the combination of nivolumab plus ipilimumab, a dual immune checkpoint inhibitor regimen, may deliver more quality-adjusted life years at lower total cost than pembrolizumab, the currently recommended first-line immunotherapy, for patients with…...

20+ hour, 53+ min ago   (69+ words) The foodborne pathogen Listeria monocytogenes has long been prized by microbiologists for its remarkable versatility: it survives refrigeration, persists on stainless steel surfaces in food-processing plants, and invades host cells with a precision that few bacteria can match. A new…...

21+ hour, 45+ min ago   (55+ words) A painful, red, blistering rash on the palms and soles is one of the most common reasons cancer patients quietly suffer through their treatment, and a new analysis of more than two decades of American drug-safety reports is now offering…...

23+ hour, 26+ min ago   (647+ words) For generations, the progress of childbirth has been tracked in a strikingly low-tech way: a clinician’s gloved fingers, inserted repeatedly into the vagina, estimating how far the cervix has opened....

1+ day, 1+ hour ago   (703+ words) Phenylalanine rarely gets top billing in discussions of molecular biology, yet this unassuming aromatic amino acid quietly underpins some of the most fundamental processes in the cell....

1+ day, 2+ hour ago   (646+ words) A groundbreaking international consensus effort has, for the first time, established detailed expert guidance on how to safely deliver CPX-351, a liposomal formulation of cytarabine and daunorubicin, to patients with therapy-related acute myeloid leukaemia (t-AML) and acute myeloid leukaemia with…...

1+ day, 2+ hour ago   (811+ words) Every few seconds inside a scanning suite, a quiet race unfolds between two forces that pull a medical image apart. On one side is the patient, whose breathing, heartbeat and small involuntary shifts blur the geometry of each frame....

1+ day, 4+ hour ago   (598+ words) For decades, neuroscientists have faced an uncomfortable trade-off: the equipment that lets them eavesdrop on the brain has too often prevented animals from behaving like themselves. Tethered recording systems, for all their fidelity, anchor a mouse to a cable, restricting…...